Searchable abstracts of presentations at key conferences in endocrinology

ea0063p431 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

Residual adrenocortical function in autoimmune addison’s disease: interim results of a cross-sectional study

Saevik AEse Bjorvatn , AEkermann Anna-Karin , Methlie Paal , Gunnar Nedrebo Bjorn , Dahle Anne Lise , Carlsen Siri , Tomkowicz Aneta , Holte Synnove Emblem , Debowska Aleksandra , Sollid Stina Therese , Jorgensen Anders , Nermone Ingrid , Gronning Kaja , Finnes Trine , Grimnes Guri , Hoybye Charlotte , Skov Jakob , Dahlqvist Per , Wahlberg Jeanette , Isaksson Magnus , Quinkler Marcus , Bensing Sophie , Oksnes Marianne , Husebye Eystein

Background: Current dogma states that in autoimmune Addison’s disease (AAD), all adrenocortical function eventually is lost. Yet growing evidence suggests that a subgroup of patients retain some self-production.Aim: To explore whether residual production of adrenocortical steroids is present in a subgroup of AAD patients.Material and methods: In an open non-randomized cross-sectional study, an interim of 22 AAD patients delive...

ea0073aep4 | Adrenal and Cardiovascular Endocrinology | ECE2021

Biomarkers of cardiovascular disease and inflammation in autoimmune addison’s disease with residual adrenocortical function

Åse Bjorvatn Sævik , Anna-Karin Åkerman , Methlie Paal , Quinkler Marcus , Anders Jørgensen , Charlotte Höybye , Debowska Aleksandra , Bjørn Gunnar Nedrebø , Dahle Anne Lise , Carlsen Siri , Tomkowicz Aneta , Synnøve Holte , Sollid Stina Therese , Nermoen Ingrid , Kaja Grønning , Dahlqvist Per , Grimnes Guri , Skov Jakob , Finnes Trine , Valland Susanna , Wahlberg Jeanette , Simunkova Katerina , Olle Kämpe , Husebye Eystein Sverre , Bensing Sophie , Marianne Øksnes

BackgroundResidual adrenocortical function (RAF) is present in one third of patients with autoimmune Addison’s disease (AAD), yet its clinical significance remains unknown.ObjectiveTo investigate if biomarker profiles of cardiovascular disease and inflammation are different in patients with AAD and RAF compared to patients without RAF and healthy controls.Material and methods<p...